Anti-M6PR Antibody

Rs. 45,619.00
SKU stj28218

General Information

Product name Anti-M6PR Antibody
Short Description Rabbit polyclonal to M6PR
Description This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-M6PR Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 27-185 of human M6PR (NP_002346.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 31 kDa
Database Links
Alternative Names M6PRCation-dependent mannose-6-phosphate receptor antibodyCD Man-6-P receptor antibodyCD-MPR antibody46 kDa mannose 6-phosphate receptor antibodyMPR 46M6PR antibodyMPR46 antibodyMPRD
Function Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes, Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex
Cellular Localization Lysosome membrane
Tissue Specificity
Swiss-Prot Key

 

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