Anti-MALT1 antibody

Rs. 50,211.00
SKU stj93995

General Information

Product name Anti-MALT1 antibody
Short Description
Description Rabbit polyclonal to MALT1.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-MALT1 antibody
Immunogen Synthesized peptide derived from human MALT1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 68 kDa
Database Links
Alternative Names Mucosa-associated lymphoid tissue lymphoma translocation protein 1 antibody
MALT lymphoma-associated translocation antibody
Paracaspase antibody
MLT antibody
Function Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
Cellular Localization Cytoplasm, perinuclear region Nucleus. Shuttles between the nucleus and cytoplasm. Found in perinuclear structures together with BCL10.
Tissue Specificity Highly expressed in peripheral blood mononuclear cells. Detected at lower levels in bone marrow, thymus and lymph node, and at very low levels in colon and lung.
Swiss-Prot Key

 

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