Anti-MANF Antibody

Rs. 45,619.00
SKU stj29085

General Information

Product name Anti-MANF Antibody
Short Description Rabbit polyclonal to MANF
Description The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-MANF Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 25-182 of human MANF (NP_006001.4).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 20.7 kDa
Database Links
Alternative Names MANFMesencephalic astrocyte-derived neurotrophic factor antibodyArginine-rich protein antibodyProtein ARMETMANF antibodyARMET antibodyARP
Function Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain.
Cellular Localization Secreted.
Tissue Specificity
Swiss-Prot Key

 

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