Anti-MAP1LC3B Antibody

Rs. 45,619.00
SKU stj27692

General Information

Product name Anti-MAP1LC3B Antibody
Short Description Rabbit polyclonal to MAP1LC3B
Description The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-MAP1LC3B Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP1LC3B (NP_073729.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 14.7 kDa
Database Links
Alternative Names MAP1LC3BMicrotubule-associated proteins 1A/1B light chain 3B antibodyAutophagy-related protein LC3 B antibodyAutophagy-related ubiquitin-like modifier LC3 B antibodyMAP1 light chain 3-like protein 2 antibodyMAP1A/MAP1B light chain 3 B antibodyMAP1A/MAP1B LC3 B antibodyMicrotubule-associated protein 1 light chain 3 betaMAP1LC3B antibodyMAP1ALC3
Function Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes), Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation, Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Cellular Localization Cytoplasm, cytoskeleton, Endomembrane system
Tissue Specificity Most abundant in heart, brain, skeletal muscle and testis, little expression observed in liver.
Swiss-Prot Key

 

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