Anti-MARCKSL1 Antibody

Rs. 45,619.00
SKU stj29212

General Information

Product name Anti-MARCKSL1 Antibody
Short Description Rabbit polyclonal to MARCKSL1
Description This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-MARCKSL1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-195 of human MARCKSL1 (NP_075385.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 19.5 kDa
Database Links
Alternative Names MARCKSL1MARCKS-related protein antibodyMARCKS-like protein 1 antibodyMacrophage myristoylated alanine-rich C kinase substrate antibodyMac-MARCKS antibodyMacMARCKSMARCKSL1 antibodyMLP antibodyMRP
Function Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation, When unphosphorylated, induces cell migration, When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration, May also affect cancer cell migration, May be involved in coupling the protein kinase C and calmodulin signal transduction systems (By similarity).
Cellular Localization Cytoplasm.
Tissue Specificity
Swiss-Prot Key

 

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