Anti-MCM5 Antibody

Rs. 45,619.00
SKU stj27502

General Information

Product name Anti-MCM5 Antibody
Short Description Rabbit polyclonal to MCM5
Description The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
Applications WB,IF
Dilution range WB 1:1000 - 1:3000
IF 1:50 - 1:200
Protein Name Anti-MCM5 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MCM5 (NP_006730.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 82.3 kDa
Database Links
Alternative Names MCM5DNA replication licensing factor MCM5 MCM5 antibodyCDC46
Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells, The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit, The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity), Interacts with MCMBP.
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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