Anti-MCPH1 Antibody

Rs. 45,619.00
SKU stj27425

General Information

Product name Anti-MCPH1 Antibody
Short Description Rabbit polyclonal to MCPH1
Description This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-MCPH1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 263-562 of human MCPH1 (NP_001166046.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 92.8 kDa
Database Links
Alternative Names MCPH1MicrocephalinMCPH1
Function Implicated in chromosome condensation and DNA damage induced cellular responses, May play a role in neurogenesis and regulation of the size of the cerebral cortex.
Cellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Tissue Specificity Expressed in fetal brain, liver and kidney.
Swiss-Prot Key

 

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