Anti-Med8 antibody

Rs. 50,211.00
SKU stj94062

General Information

Product name Anti-Med8 antibody
Short Description
Description Rabbit polyclonal to Med8.
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:5000
Protein Name Anti-Med8 antibody
Immunogen Synthesized peptide derived from human Med8
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 29 kDa
Database Links
Alternative Names Med8
Mediator of RNA polymerase II transcription subunit 8 antibody
Activator-recruited cofactor 32 kDa component antibody
ARC32 antibody
Mediator complex subunit 8 antibody
Function Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May play a role as a target recruitment subunit in E3 ubiquitin-protein ligase complexes and thus in ubiquitination and subsequent proteasomal degradation of target proteins.
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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