General Information
Product name | Anti-mGluR-2/3 antibody |
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Short Description | |
Description | Rabbit polyclonal to mGluR-2/3. |
Applications | WB,IHC,ELISA |
Dilution range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000 |
Protein Name | Anti-mGluR-2/3 antibody |
Immunogen | Synthesized peptide derived from human mGluR-2/3 |
Storage Instruction | Store at -20°C, and avoid repeat freeze-thaw cycles. |
Type of Usage | For Research Use Only (RUO). |
Product Properties
Host | Rabbit |
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Clonality | Polyclonal |
Reactivity | Mouse,Rat |
Conjugation | Unconjugated |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Isotype | IgG |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Target
Gene ID | |
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Gene Symbol | |
Molecular Weight | 100 kDa |
Database Links | |
Alternative Names | mGluR-2/3 Metabotropic glutamate receptor 2 antibody mGluR2 antibody GPRC1B antibody MGLUR2 antibody |
Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
Cellular Localization | Cell membrane. Multi-pass membrane protein. Cell junction, synapse Cell projection, dendrite |
Tissue Specificity | Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. |
Swiss-Prot Key |