General Information
| Product name | Anti-mGluR-2/3 antibody |
|---|---|
| Short Description | |
| Description | Rabbit polyclonal to mGluR-2/3. |
| Applications | WB,IHC,ELISA |
| Dilution range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000 |
| Protein Name | Anti-mGluR-2/3 antibody |
| Immunogen | Synthesized peptide derived from human mGluR-2/3 |
| Storage Instruction | Store at -20°C, and avoid repeat freeze-thaw cycles. |
| Type of Usage | For Research Use Only (RUO). |
Product Properties
| Host | Rabbit |
|---|---|
| Clonality | Polyclonal |
| Reactivity | Mouse,Rat |
| Conjugation | Unconjugated |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
Target
| Gene ID | |
|---|---|
| Gene Symbol | |
| Molecular Weight | 100 kDa |
| Database Links | |
| Alternative Names | mGluR-2/3 Metabotropic glutamate receptor 2 antibody mGluR2 antibody GPRC1B antibody MGLUR2 antibody |
| Function | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization. |
| Cellular Localization | Cell membrane. Multi-pass membrane protein. Cell junction, synapse Cell projection, dendrite |
| Tissue Specificity | Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain. |
| Swiss-Prot Key |