Anti-MKS1 Antibody

Rs. 45,619.00
SKU stj26874

General Information

Product name Anti-MKS1 Antibody
Short Description Rabbit polyclonal to MKS1
Description The protein encoded by this gene localizes to the basal body and is required for formation of the primary cilium in ciliated epithelial cells. Mutations in this gene result in Meckel syndrome type 1 and in Bardet-Biedl syndrome type 13. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-MKS1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 150-300 of human MKS1 (NP_060247.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 64.5 kDa
Database Links
Alternative Names MKS1Meckel syndrome type 1 proteinMKS1
Function Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes, Involved in centrosome migration to the apical cell surface during early ciliogenesis, Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication, Required for cell branching morphology.
Cellular Localization Cytoplasm, cytoskeleton, cilium basal body, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Tissue Specificity
Swiss-Prot Key

 

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