Anti-MLPH Antibody

Rs. 45,619.00
SKU stj28739

General Information

Product name Anti-MLPH Antibody
Short Description Rabbit polyclonal to MLPH
Description This gene encodes a member of the exophilin subfamily of Rab effector proteins. The protein forms a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. A similar protein complex in mouse functions to tether pigment-producing organelles called melanosomes to the actin cytoskeleton in melanocytes, and is required for visible pigmentation in the hair and skin. A mutation in this gene results in Griscelli syndrome type 3, which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-MLPH Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 301-600 of human MLPH (NP_077006.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 65.9 kDa
Database Links
Alternative Names MLPHMelanophilin antibodyExophilin-3 antibodySlp homolog lacking C2 domains a antibodySlaC2-a antibodySynaptotagmin-like protein 2aMLPH antibodySLAC2A
Function Rab effector protein involved in melanosome transport, Serves as link between melanosome-bound RAB27A and the motor protein MYO5A.
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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