Anti-MMP19 Antibody

Rs. 45,619.00
SKU stj28740

General Information

Product name Anti-MMP19 Antibody
Short Description Rabbit polyclonal to MMP19
Description This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-MMP19 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 209-508 of human MMP19 (NP_002420.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 57.4 kDa
Database Links
Alternative Names MMP19Matrix metalloproteinase-19 antibodyMMP-19MMP19 antibodyMMP18 antibodyRASI
Function Endopeptidase that degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease), May also play a role in neovascularization or angiogenesis, Hydrolyzes collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin.
Cellular Localization Secreted, extracellular space, extracellular matrix
Tissue Specificity Expressed in mammary gland, placenta, lung, pancreas, ovary, small intestine, spleen, thymus, prostate, testis colon, heart and blood vessel walls, not detected in brain and peripheral blood leukocytes, also expressed in the synovial fluid of normal and rheumatoid patients.
Swiss-Prot Key

 

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