Anti-MYH7 Antibody

Rs. 45,619.00
SKU stj29702

General Information

Product name Anti-MYH7 Antibody
Short Description Rabbit polyclonal to MYH7
Description Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-MYH7 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1766-1935 of human MYH7 (NP_000248.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 223.1 kDa
Database Links
Alternative Names MYH7Myosin-7 antibodyMyosin heavy chain 7 antibodyMyosin heavy chain slow isoform antibodyMyHC-slow antibodyMyosin heavy chain antibodycardiac muscle beta isoform antibodyMyHC-betaMYH7 antibodyMYHCB
Function Myosins are actin-based motor molecules with ATPase activity essential for muscle contraction, Forms regular bipolar thick filaments that, together with actin thin filaments, constitute the fundamental contractile unit of skeletal and cardiac muscle.
Cellular Localization Cytoplasm, myofibril
Tissue Specificity Both wild type and variant gln-403 are detected in skeletal muscle (at protein level).
Swiss-Prot Key

 

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