Anti-MYO1C Antibody

Rs. 45,619.00
SKU stj29016

General Information

Product name Anti-MYO1C Antibody
Short Description Rabbit polyclonal to MYO1C
Description This gene encodes a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane. Multiple transcript variants encoding different isoforms have been found for this gene. The related gene myosin IE has been referred to as myosin IC in the literature, but it is a distinct locus on chromosome 19.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:100
Protein Name Anti-MYO1C Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_203693.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 121.7 kDa
Database Links
Alternative Names MYO1CUnconventional myosin-Ic antibodyMyosin I beta antibodyMMI-beta antibodyMMIbMYO1C
Function Myosins are actin-based motor molecules with ATPase activity, Unconventional myosins serve in intracellular movements, Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments, Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane, Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex, Acts as a mediator of adaptation of mechanoelectrical transduction in stereocilia of vestibular hair cells, Binds phosphoinositides and links the actin cytoskeleton to cellular membranes.
Cellular Localization Cytoplasm, Nucleus, nucleoplasm, Nucleus, nucleolus, Nucleus, nuclear pore complex.
Tissue Specificity
Swiss-Prot Key

 

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