Anti-MYOT Antibody

Rs. 45,619.00
SKU stj28522

General Information

Product name Anti-MYOT Antibody
Short Description Rabbit polyclonal to MYOT
Description This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100
Protein Name Anti-MYOT Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 259-314 of human MYOT (NP_001129412.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 55.4 kDa
Database Links
Alternative Names MYOTMyotilin antibody57 kDa cytoskeletal protein antibodyMyofibrillar titin-like Ig domains protein antibodyTitin immunoglobulin domain proteinMYOT antibodyTTID
Function Component of a complex of multiple actin cross-linking proteins, Involved in the control of myofibril assembly and stability at the Z lines in muscle cells.
Cellular Localization Cell membrane, sarcolemma.
Tissue Specificity Expressed in skeletal muscle (at protein level), expressed in skeletal muscle, heart, bone marrow and thyroid gland.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed