Anti-NCL Antibody

Rs. 45,619.00
SKU stj29927

General Information

Product name Anti-NCL Antibody
Short Description Rabbit polyclonal to NCL
Description Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-NCL Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 461-710 of human NCL (NP_005372.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 76.6 kDa
Database Links
Alternative Names NCLNucleolin antibodyProtein C23NCL
Function Nucleolin is the major nucleolar protein of growing eukaryotic cells, It is found associated with intranucleolar chromatin and pre-ribosomal particles, It induces chromatin decondensation by binding to histone H1, It is thought to play a role in pre-rRNA transcription and ribosome assembly, May play a role in the process of transcriptional elongation, Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
Cellular Localization Nucleus, nucleolus, Cytoplasm.
Tissue Specificity
Swiss-Prot Key

 

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