Anti-NDEL1 Antibody

Rs. 68,577.00
SKU stj71835

General Information

Product name Anti-NDEL1 Antibody
Short Description Goat polyclonal to NDEL1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-NDEL1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 38.4 kDa
Database Links
Alternative Names NDEL1Nuclear distribution protein nudE-like 1 antibodyProtein Nudel antibodyMitosin-associated protein 1NDEL1 antibodyEOPA antibodyMITAP1 antibodyNUDEL
Function Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome, May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome, Also positively regulates the activity of the minus-end directed microtubule motor protein dynein, May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends, Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome, Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate, Plays a role, together with DISC1, in the regulation of neurite outgrowth, Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1, Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL, Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity),
Cellular Localization Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Chromosome, centromere, kinetochore, Cytoplasm, cytoskeleton, spindle,
Tissue Specificity Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle,
Swiss-Prot Key

 

You recently viewed

Clear recently viewed