Anti-NDRG2 antibody

Rs. 50,211.00
SKU stj94369

General Information

Product name Anti-NDRG2 antibody
Short Description
Description Rabbit polyclonal to NDRG2.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-NDRG2 antibody
Immunogen Synthesized peptide derived from human NDRG2
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 40.798 kDa
Database Links
Alternative Names Protein NDRG2 antibody
N-myc downstream-regulated gene 2 protein antibody
Protein Syld709613 antibody
Protein NDRG2, N-terminally processed antibody
KIAA1248 antibody
SYLD antibody
Function Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Cellular Localization Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone. In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons .
Tissue Specificity Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver. Expressed in dendritic cells, but not in other blood cells. Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level).
Swiss-Prot Key

 

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