Anti-PVRL1 Antibody

Rs. 45,619.00
SKU stj25240

General Information

Product name Anti-PVRL1 Antibody
Short Description Rabbit polyclonal to NECTIN1
Description This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PVRL1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 70-350 of human PVRL1 (NP_002846.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 57.2 kDa
Database Links
Alternative Names NECTIN1Nectin-1 antibodyHerpes virus entry mediator C antibodyHerpesvirus entry mediator C antibodyHveC antibodyHerpesvirus Ig-like receptor antibodyHIgR antibodyNectin cell adhesion molecule 1 antibodyPoliovirus receptor-related protein 1 antibodyCD antigen CD111NECTIN1 antibodyHVEC antibodyPRR1 antibodyPVRL1
Function Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers, Heterophilic interactions have been detected between NECTIN1 and NECTIN3 and between NECTIN1 and NECTIN4, Has some neurite outgrowth-promoting activity.
Cellular Localization Isoform Alpha: Cell membrane
Tissue Specificity
Swiss-Prot Key

 

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