Anti-NELFCD Antibody

Rs. 68,577.00
SKU stj72414

General Information

Product name Anti-NELFCD Antibody
Short Description Goat polyclonal to NELFCD
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-NELFCD Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 66.2 kDa
Database Links
Alternative Names NELFCDNegative elongation factor C/D antibodyNELF-C/D antibodyTH1-like proteinNELFCD antibodyNELFD antibodyTH1 antibodyTH1L antibodyHSPC130
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II, The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex, The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II, Binds RNA which may help to stabilize the NELF complex on nucleic acid, In vitro, the NELFA:NELFCD subcomplex binds to ssDNA and ssRNA in a sequence- and structure-dependent manner,
Cellular Localization Nucleus
Tissue Specificity Widely expressed, expressed in heart, brain, lung, placenta, liver, skeletal and cardiac muscle, adrenal, thyroid, kidney and pancreas,
Swiss-Prot Key

 

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