Anti-NFATC3 Antibody

Rs. 45,619.00
SKU stj28749

General Information

Product name Anti-NFATC3 Antibody
Short Description Rabbit polyclonal to NFATC3
Description The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-NFATC3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human NFATC3 (NP_775188.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 115.6 kDa
Database Links
Alternative Names NFATC3Nuclear factor of activated T-cells antibodycytoplasmic 3 antibodyNF-ATc3 antibodyNFATc3 antibodyNFATx antibodyT-cell transcription factor NFAT4 antibodyNF-AT4NFATC3 antibodyNFAT4
Function Acts as a regulator of transcriptional activation, Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2.
Cellular Localization Cytoplasm.
Tissue Specificity Isoform 1 is predominantly expressed in thymus and is also found in peripheral blood leukocytes and kidney, isoform 2 is predominantly expressed in skeletal muscle and is also found in thymus, kidney, testis, spleen, prostate, ovary, small intestine, heart, placenta and pancreas, isoform 3 is expressed in thymus and kidney, isoform 4 is expressed in thymus and skeletal muscle
Swiss-Prot Key

 

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