Anti-NFIL3 Antibody

Rs. 45,619.00
SKU stj29433

General Information

Product name Anti-NFIL3 Antibody
Short Description Rabbit polyclonal to NFIL3
Description The protein encoded by this gene is a transcriptional regulator that binds as a homodimer to activating transcription factor (ATF) sites in many cellular and viral promoters. The encoded protein represses PER1 and PER2 expression and therefore plays a role in the regulation of circadian rhythm. Three transcript variants encoding the same protein have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-NFIL3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 133-462 of human NFIL3 (NP_005375.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 51.5 kDa
Database Links
Alternative Names NFIL3Nuclear factor interleukin-3-regulated protein antibodyE4 promoter-binding protein 4 antibodyInterleukin-3 promoter transcriptional activator antibodyInterleukin-3-binding protein 1 antibodyTranscriptional activator NF-IL3ANFIL3 antibodyE4BP4 antibodyIL3BP1
Function Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters, Represses transcription from promoters with activating transcription factor (ATF) sites, Represses promoter activity in osteoblasts (By similarity), Represses transcriptional activity of PER1 (By similarity), Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity), Activates transcription from the interleukin-3 promoter in T-cells, Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity), Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity), Protects pro-B cells from programmed cell death (By similarity).
Cellular Localization Nucleus
Tissue Specificity Expressed in bladder stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland, bone marrow and muscle.
Swiss-Prot Key

 

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