Anti-NFYB Antibody

Rs. 45,619.00
SKU stj29434

General Information

Product name Anti-NFYB Antibody
Short Description Rabbit polyclonal to NFYB
Description The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-NFYB Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human NFYB (NP_006157.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 22.8 kDa
Database Links
Alternative Names NFYBNuclear transcription factor Y subunit beta antibodyCAAT box DNA-binding protein subunit B antibodyNuclear transcription factor Y subunit B antibodyNF-YBNFYB antibodyHAP3
Function Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes, NF-Y can function as both an activator and a repressor, depending on its interacting cofactors
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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