Anti-NGB Antibody

Rs. 45,619.00
SKU stj28560

General Information

Product name Anti-NGB Antibody
Short Description Rabbit polyclonal to NGB
Description This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-NGB Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-151 of human NGB (NP_067080.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 16.9 kDa
Database Links
Alternative Names NGBNeuroglobinNGB
Function Involved in oxygen transport in the brain, Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom, Not capable of penetrating cell membranes, The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase, Involved in neuroprotection during oxidative stress, May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.
Cellular Localization Perikaryon, Cytoplasm, Mitochondrion
Tissue Specificity Predominantly expressed in brain, the strongest expression is seen in the frontal lobe, the subthalamic nucleus and the thalamus.
Swiss-Prot Key

 

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