Anti-NLGN2 Antibody

Rs. 68,577.00
SKU stj71114

General Information

Product name Anti-NLGN2 Antibody
Short Description Goat polyclonal to NLGN2
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-NLGN2 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 90.8 kDa
Database Links
Alternative Names NLGN2Neuroligin-2NLGN2 antibodyKIAA1366
Function Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members, Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells, Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors), Functions by recruiting and clustering synaptic proteins, Promotes clustering of postsynaptic GABRG2 and GPHN, Modulates signaling by inhibitory synapses, and thereby plays a role in controlling the ratio of signaling by excitatory and inhibitory synapses and information processing, Required for normal signal amplitude from inhibitory synapses, but is not essential for normal signal frequency, May promote the initial formation of synapses, but is not essential for this, In vitro, triggers the de novo formation of presynaptic structures, Mediates cell-cell interactions between Langerhans beta cells and modulates insulin secretion (By similarity),
Cellular Localization Cell membrane,
Tissue Specificity Expressed in the blood vessel walls, detected in colon, brain and pancreas islets of langerhans (at protein level), detected in brain, and at lower levels in pancreas islet beta cells,
Swiss-Prot Key

 

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