Anti-NME1 Antibody

Rs. 68,577.00
SKU stj73079

General Information

Product name Anti-NME1 Antibody
Short Description Goat polyclonal to NME1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-NME1 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 17.1 kDa
Database Links
Alternative Names NME1Nucleoside diphosphate kinase A antibodyNDK A antibodyNDP kinase ANME1 antibodyNDPKA antibodyNM23
Function Major role in the synthesis of nucleoside triphosphates other than ATP, The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate, Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities, Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression, Required for neural development including neural patterning and cell fate determination, During GZMA-mediated cell death, works in concert with TREX1, NME1 nicks one strand of DNA and TREX1 removes bases from the free 3' end to enhance DNA damage and prevent DNA end reannealing and rapid repair,
Cellular Localization Cytoplasm,
Tissue Specificity Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus, expressed in lung carcinoma cell lines but not in normal lung tissues, isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation,
Swiss-Prot Key

 

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