Anti-NOTCH1 Antibody

Rs. 68,577.00
SKU stj73604

General Information

Product name Anti-NOTCH1 Antibody
Short Description Goat polyclonal to NOTCH1
Description
Applications ELISA, IF
Dilution range
Protein Name Anti-NOTCH1 Antibody
Immunogen N Terminus (near)
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 272.5 kDa
Database Links
Alternative Names NOTCH1Neurogenic locus notch homolog protein 1 antibodyNotch 1 antibodyhN1 antibodyTranslocation-associated notch protein TAN-1NOTCH1 antibodyTAN1
Function Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination, Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus, Affects the implementation of differentiation, proliferation and apoptotic programs, Involved in angiogenesis
Cellular Localization Cell membrane
Tissue Specificity In fetal tissues most abundant in spleen, brain stem and lung, also present in most adult tissues where it is found mainly in lymphoid tissues
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF