Anti-NOX5 Antibody

Rs. 45,619.00
SKU stj29216

General Information

Product name Anti-NOX5 Antibody
Short Description Rabbit polyclonal to NOX5
Description This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-NOX5 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 661-765 of human NOX5 (NP_078781.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 86.4 kDa
Database Links
Alternative Names NOX5NADPH oxidase 5 NOX5
Function Calcium-dependent NADPH oxidase that generates superoxide, Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa, May play a role in cell growth and apoptosis, Isoform v2 and isoform v5 are involved in endothelial generation of reactive oxygen species (ROS), proliferation and angiogenesis and contribute to endothelial response to thrombin.
Cellular Localization Membrane
Tissue Specificity Mainly expressed in pachytene spermatocytes of testis and in lymphocyte-rich areas of spleen and lymph nodes, isoform v1 is expressed in spleen, isoform v2 is expressed in testis, also detected in ovary, placenta, pancreas, cardiac fibroblasts, expressed in b-cells and prostate malignant cells, isoform v1 and isoform v3 are expressed in epithelial colorectal adenocarcinoma cells, isoform v2 and isoform v4 are expressed in endothelial cells, isoform v1, isoform v2, isoform v3 and isoform v4 are expressed in pulmonary artery smooth muscle cells, isoform v2 and isoform v5 are expressed in microvascular endothelial cells (at protein level).
Swiss-Prot Key

 

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