Anti-Nprl3 Antibody

Rs. 68,577.00
SKU stj72691

General Information

Product name Anti-Nprl3 Antibody
Short Description Goat polyclonal to Nprl3 (mouse)
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-Nprl3 Antibody
Immunogen internal region (N Terminus)
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 63.6 kDa
Database Links
Alternative Names Anti-Nprl3 (mouse) Antibody
Function As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway, The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling, The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway,
Cellular Localization Lysosome membrane
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed