Anti-NR2E3 Antibody

Rs. 45,619.00
SKU stj27990

General Information

Product name Anti-NR2E3 Antibody
Short Description Rabbit polyclonal to NR2E3
Description This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-NR2E3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 121-410 of human NR2E3 (NP_055064.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 44.7 kDa
Database Links
Alternative Names NR2E3Photoreceptor-specific nuclear receptor antibodyNuclear receptor subfamily 2 group E member 3 antibodyRetina-specific nuclear receptorNR2E3 antibodyPNR antibodyRNR
Function Orphan nuclear receptor of retinal photoreceptor cells, Transcriptional factor that is an activator of rod development and repressor of cone development, Binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit, Enhances rhodopsin expression, Represses M- and S-cone opsin expression.
Cellular Localization Nucleus
Tissue Specificity Eye specific
Swiss-Prot Key

 

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