Anti-NR5A2 Antibody

Rs. 68,577.00
SKU stj72073

General Information

Product name Anti-NR5A2 Antibody
Short Description Goat polyclonal to NR5A2
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-NR5A2 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 61.3 kDa
Database Links
Alternative Names NR5A2Nuclear receptor subfamily 5 group A member 2 antibodyAlpha-1-fetoprotein transcription factor antibodyB1-binding factor antibodyhB1F antibodyCYP7A promoter-binding factor antibodyHepatocytic transcription factor antibodyLiver receptor homolog 1 antibodyLRH-1NR5A2 antibodyB1F antibodyCPF antibodyFTF
Function Nuclear receptor that acts as a key metabolic sensor by regulating the expression of genes involved in bile acid synthesis, cholesterol homeostasis and triglyceride synthesis, Together with the oxysterol receptors NR1H3/LXR-alpha and NR1H2/LXR-beta, acts as an essential transcriptional regulator of lipid metabolism, Plays an anti-inflammatory role during the hepatic acute phase response by acting as a corepressor: inhibits the hepatic acute phase response by preventing dissociation of the N-Cor corepressor complex expression in liver, May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development,
Cellular Localization Nucleus
Tissue Specificity Abundantly expressed in pancreas, less in liver, very low levels in heart and lung, expressed in the hep-g2 cell line, isoform 1 and isoform 2 seem to be present in fetal and adult liver and hep-g2 cells
Swiss-Prot Key

 

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