Anti-NRF1 Antibody

Rs. 45,619.00
SKU stj27493

General Information

Product name Anti-NRF1 Antibody
Short Description Rabbit polyclonal to NRF1
Description This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for 'nuclear factor (erythroid-derived 2)-like 1' which has an official symbol of NFE2L1.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-NRF1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 240-449 of human NRF1 (NP_001035199.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.5 kDa
Database Links
Alternative Names NRF1Nuclear respiratory factor 1 antibodyNRF-1 antibodyAlpha palindromic-binding protein antibodyAlpha-palNRF1
Function Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene, Links the transcriptional modulation of key metabolic genes to cellular growth and development, Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication
Cellular Localization Nucleus
Tissue Specificity Ubiquitously expressed with strongest expression in skeletal muscle
Swiss-Prot Key

 

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