Anti-OAS1 Antibody

Rs. 68,577.00
SKU stj73370

General Information

Product name Anti-OAS1 Antibody
Short Description Goat polyclonal to OAS1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-OAS1 Antibody
Immunogen internal region (near C terminus)
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 46 kDa
Database Links
Alternative Names OAS12'-5'-oligoadenylate synthase 1 antibody(2-5' antibodyoligo(A antibodysynthase 1 antibody2-5A synthase 1OAS1 antibodyOIAS
Function Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response, In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation, Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation, Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication, Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L, The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L,
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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