Anti-OCLN Antibody

Rs. 61,689.00
SKU stj28910

General Information

Product name Anti-OCLN Antibody
Short Description Rabbit polyclonal to OCLN
Description This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-OCLN Antibody
Immunogen A synthetic peptide of human OCLN
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 59.1 kDa
Database Links
Alternative Names OCLNOccludinOCLN
Function May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier, It is able to induce adhesion when expressed in cells lacking tight junctions.
Cellular Localization Cell membrane
Tissue Specificity Localized at tight junctions of both epithelial and endothelial cells, highly expressed in kidney, not detected in testis
Swiss-Prot Key

 

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