Anti-ORAI1 Antibody

Rs. 45,619.00
SKU stj29548

General Information

Product name Anti-ORAI1 Antibody
Short Description Rabbit polyclonal to ORAI1
Description The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
Applications WB
Dilution range WB 1:200 - 1:2000
Protein Name Anti-ORAI1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 202-301 of human ORAI1 (NP_116179.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 32.7 kDa
Database Links
Alternative Names ORAI1Calcium release-activated calcium channel protein 1 antibodyProtein orai-1 antibodyTransmembrane protein 142AORAI1 antibodyCRACM1 antibodyTMEM142A
Function Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1.
Cellular Localization Cell membrane.
Tissue Specificity
Swiss-Prot Key

 

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