Anti-P2RY2 Antibody

Rs. 45,619.00
SKU stj28346

General Information

Product name Anti-P2RY2 Antibody
Short Description Rabbit polyclonal to P2RY2
Description The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-P2RY2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 278-377 of human P2RY2 (NP_788086.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 42.3 kDa
Database Links
Alternative Names P2RY2P2Y purinoceptor 2 antibodyP2Y2 antibodyATP receptor antibodyP2U purinoceptor 1 antibodyP2U1 antibodyP2U receptor 1 antibodyPurinergic receptorP2RY2 antibodyP2RU1
Function Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system, The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP
Cellular Localization Cell membrane
Tissue Specificity Spleen, testis, kidney, liver, lung, heart and brain
Swiss-Prot Key

 

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