Anti-PALLD Antibody

Rs. 50,211.00
SKU stj27480

General Information

Product name Anti-PALLD Antibody
Short Description Rabbit polyclonal to PALLD
Description This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants.
Applications WB,IHC,IF,IP,FC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:20 - 1:50
FC 1:20 - 1:50
Protein Name Anti-PALLD Antibody
Immunogen Recombinant Protein of human PALLD
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 150.6 kDa
Database Links
Alternative Names PALLDPalladin antibodySIH002 antibodySarcoma antigen NY-SAR-77PALLD antibodyKIAA0992 antibodyCGI-151
Function Cytoskeletal protein required for organization of normal actin cytoskeleton, Roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types, May function as a scaffolding molecule with the potential to influence both actin polymerization and the assembly of existing actin filaments into higher-order arrays, Binds to proteins that bind to either monomeric or filamentous actin, Localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles, Different isoforms may have functional differences, Involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation, Involved in targeting ACTN to specific subcellular foci.
Cellular Localization Cytoplasm, cytoskeleton.
Tissue Specificity Detected in both muscle and non-muscle tissues, high expression in prostate, ovary, colon, and kidney, not detected in spleen, skeletal muscle, lung and peripheral blood lymphocytes (at protein level), protein is overexpressed in fa6, hpaf, imim-pc2, suit-2 and panctu-ii sporadic pancreatic cancer cell lines.
Swiss-Prot Key

 

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