Anti-PARD6B Antibody

Rs. 45,619.00
SKU stj27055

General Information

Product name Anti-PARD6B Antibody
Short Description Rabbit polyclonal to PARD6B
Description This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cytoplasmic protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex.
Applications WB
Dilution range WB 1:1000 - 1:4000
Protein Name Anti-PARD6B Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 253-372 of human PARD6B (NP_115910.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.2 kDa
Database Links
Alternative Names PARD6BPartitioning defective 6 homolog beta antibodyPAR-6 beta antibodyPAR-6BPARD6B antibodyPAR6B
Function Adapter protein involved in asymmetrical cell division and cell polarization processes, Probably involved in formation of epithelial tight junctions, Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly, The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins
Cellular Localization Cytoplasm, Cell membrane
Tissue Specificity Expressed in pancreas and in both adult and fetal kidney, weakly expressed in placenta and lung, not expressed in other tissues
Swiss-Prot Key

 

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