Anti-PCBD1 Antibody

Rs. 45,619.00
SKU stj28475

General Information

Product name Anti-PCBD1 Antibody
Short Description Rabbit polyclonal to PCBD1
Description This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-PCBD1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-104 of human PCBD1 (NP_000272.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 12 kDa
Database Links
Alternative Names PCBD1Pterin-4-alpha-carbinolamine dehydratase antibodyPHSPCBD1 antibodyDCOH antibodyPCBD
Function Involved in tetrahydrobiopterin biosynthesis, Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2, Coactivator for HNF1A-dependent transcription, Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity
Cellular Localization Cytoplasm, Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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