Anti-PCK1 Antibody

Rs. 45,619.00
SKU stj24916

General Information

Product name Anti-PCK1 Antibody
Short Description Rabbit polyclonal to PCK1
Description This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Applications WB,IHC
Dilution range WB 1:1000 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-PCK1 Antibody
Immunogen A synthetic peptide of human PCK1
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 69.2 kDa
Database Links
Alternative Names PCK1Phosphoenolpyruvate carboxykinase antibodycytosolic antibodyPEPCK-CPCK1 antibodyPEPCK1
Function Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
Cellular Localization Cytoplasm
Tissue Specificity Major sites of expression are liver, kidney and adipocytes
Swiss-Prot Key

 

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