Anti-PCNA Antibody

Rs. 68,577.00
SKU stj72849

General Information

Product name Anti-PCNA Antibody
Short Description Goat polyclonal to PCNA
Description
Applications ELISA, WB, EIA
Dilution range
Protein Name Anti-PCNA Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 28.8 kDa
Database Links
Alternative Names PCNAProliferating cell nuclear antigen antibodyPCNA antibodyCyclinPCNA
Function Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand, Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities, Has to be loaded onto DNA in order to be able to stimulate APEX2, Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion,
Cellular Localization Nucleus,
Tissue Specificity
Swiss-Prot Key

 

You recently viewed

Clear recently viewed