Anti-PCSK1N Antibody

Rs. 57,098.00
SKU stj73063

General Information

Product name Anti-PCSK1N Antibody
Short Description Goat polyclonal to PCSK1N
Description
Applications ELISA, IHC
Dilution range
Protein Name Anti-PCSK1N Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 27.4 kDa
Database Links
Alternative Names PCSK1NProSAAS antibodyProprotein convertase subtilisin/kexin type 1 inhibitor antibodyProprotein convertase 1 inhibitor antibodypro-SAASPCSK1N
Function May function in the control of the neuroendocrine secretory pathway, Proposed be a specific endogenous inhibitor of PCSK1, ProSAAS and Big PEN-LEN, both containing the C-terminal inhibitory domain, but not the further processed peptides reduce PCSK1 activity in the endoplasmic reticulum and Golgi, It reduces the activity of the 84 kDa form but not the autocatalytically derived 66 kDa form of PCSK1, Subsequent processing of proSAAS may eliminate the inhibition, Slows down convertase-mediated processing of proopiomelanocortin and proenkephalin, May control the intracellular timing of PCSK1 rather than its total level of activity, The function of the processed secreted peptides is not known (By similarity),
Cellular Localization Secreted,
Tissue Specificity Expressed in brain and pancreas,
Swiss-Prot Key

 

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