Anti-PDCD1 Antibody

Rs. 45,619.00
SKU stj27553

General Information

Product name Anti-PDCD1 Antibody
Short Description Rabbit polyclonal to PDCD1
Description This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PDCD1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 21-170 of human PDCD1 (NP_005009.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 31.6 kDa
Database Links
Alternative Names PDCD1Programmed cell death protein 1 antibodyProtein PD-1 antibodyhPD-1 antibodyCD antigen CD279PDCD1 antibodyPD1
Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance, Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner, Possible cell death inducer, in association with other factors.
Cellular Localization Membrane
Tissue Specificity
Swiss-Prot Key

 

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