Anti-PDCD10 Antibody

Rs. 45,619.00
SKU stj24923

General Information

Product name Anti-PDCD10 Antibody
Short Description Rabbit polyclonal to PDCD10
Description This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Applications IHC
Dilution range IHC 1:50 - 1:100
Protein Name Anti-PDCD10 Antibody
Immunogen A synthetic peptide of human PDCD10
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 24.7 kDa
Database Links
Alternative Names PDCD10Programmed cell death protein 10 antibodyCerebral cavernous malformations 3 protein antibodyTF-1 cell apoptosis-related protein 15PDCD10 antibodyCCM3 antibodyTFAR15
Function Promotes cell proliferation, Modulates apoptotic pathways, Increases mitogen-activated protein kinase activity and STK26 activity.
Cellular Localization Cytoplasm, Golgi apparatus membrane
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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