Anti-PDCD4 Antibody

Rs. 68,577.00
SKU stj72822

General Information

Product name Anti-PDCD4 Antibody
Short Description Goat polyclonal to PDCD4
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-PDCD4 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 51.7 kDa
Database Links
Alternative Names PDCD4Programmed cell death protein 4 antibodyNeoplastic transformation inhibitor protein antibodyNuclear antigen H731-like antibodyProtein 197/15aPDCD4 antibodyH731
Function Inhibits translation initiation and cap-dependent translation, May excert its function by hindering the interaction between EIF4A1 and EIF4G, Inhibits the helicase activity of EIF4A, Modulates the activation of JUN kinase, Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription, May play a role in apoptosis, Tumor suppressor, Inhibits tumor promoter-induced neoplastic transformation, Binds RNA (By similarity),
Cellular Localization Nucleus,
Tissue Specificity Up-regulated in proliferative cells, highly expressed in epithelial cells of the mammary gland, reduced expression in lung cancer and colon carcinoma,
Swiss-Prot Key

 

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