Anti-PDE1C Antibody

Rs. 61,689.00
SKU stj24931

General Information

Product name Anti-PDE1C Antibody
Short Description Rabbit polyclonal to PDE1C
Description This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-PDE1C Antibody
Immunogen A synthetic Peptide of human PDE1C
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 80.8 kDa
Database Links
Alternative Names PDE1CCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C antibodyCam-PDE 1CPDE1C
Function Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes, Has a high affinity for both cAMP and cGMP
Cellular Localization
Tissue Specificity Expressed in several tissues, including brain and heart
Swiss-Prot Key

 

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