Anti-PDK1 Antibody

Rs. 68,577.00
SKU stj70803

General Information

Product name Anti-PDK1 Antibody
Short Description Goat polyclonal to PDK1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-PDK1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 49.2 kDa
Database Links
Alternative Names PDK1 kinase isozyme 1 antibodymitochondrial PDK1 antibodyPDHK1
Function Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2, This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate, Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia, Protects cells against apoptosis in response to hypoxia and oxidative stress,
Cellular Localization Mitochondrion matrix
Tissue Specificity Expressed predominantly in the heart, detected at lower levels in liver, skeletal muscle and pancreas,
Swiss-Prot Key

 

You recently viewed

Clear recently viewed
Print Friendly and PDF