Anti-PDLIM3 Antibody

Rs. 45,619.00
SKU stj28430

General Information

Product name Anti-PDLIM3 Antibody
Short Description Rabbit polyclonal to PDLIM3
Description The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-PDLIM3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 70-230 of human PDLIM3 (NP_001107579.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 39.2 kDa
Database Links
Alternative Names PDLIM3PDZ and LIM domain protein 3 antibodyActinin-associated LIM protein antibodyAlpha-actinin-2-associated LIM proteinPDLIM3 antibodyALP
Function May play a role in the organization of actin filament arrays within muscle cells.
Cellular Localization Cytoplasm, myofibril, sarcomere, Z line.
Tissue Specificity Isoform 1 is highly expressed in differentiated skeletal muscle, isoform 2 is heart-specific.
Swiss-Prot Key

 

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