Anti-PDS5A Antibody

Rs. 61,689.00
SKU stj24952

General Information

Product name Anti-PDS5A Antibody
Short Description Rabbit polyclonal to PDS5A
Description The protein encoded by this gene binds to the cohesin complex and associates with chromatin through most of the cell cycle. The encoded protein may play a role in regulating sister chromatid cohesion during mitosis. Two transcript variants encoding different isoforms have been found for this gene.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-PDS5A Antibody
Immunogen A synthetic Peptide of human PDS5A
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 150.8 kDa
Database Links
Alternative Names PDS5ASister chromatid cohesion protein PDS5 homolog A antibodyCell proliferation-inducing gene 54 protein antibodySister chromatid cohesion protein 112 antibodySCC-112PDS5A antibodyKIAA0648 antibodyPDS5 antibodyPIG54
Function Probable regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin, May couple sister chromatid cohesion during mitosis to DNA replication, Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.
Cellular Localization Nucleus
Tissue Specificity Highest level in colon, low levels in lung, ovary, breast and kidney, reduced level in renal tumor tissue, isoform 2 is expressed in kidney.
Swiss-Prot Key

 

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