Anti-PEBP1 Antibody

Rs. 45,619.00
SKU stj24954

General Information

Product name Anti-PEBP1 Antibody
Short Description Rabbit polyclonal to PEBP1
Description This gene encodes a member of the phosphatidylethanolamine-binding family of proteins and has been shown to modulate multiple signaling pathways, including the MAP kinase (MAPK), NF-kappa B, and glycogen synthase kinase-3 (GSK-3) signaling pathways. The encoded protein can be further processed to form a smaller cleavage product, hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in neural development. This gene has been implicated in numerous human cancers and may act as a metastasis suppressor gene. Multiple pseudogenes of this gene have been identified in the genome.
Applications WB,IF,IP,RIP
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
IP 1:20 - 1:50
RIP 1:20 - 1:50
Protein Name Anti-PEBP1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human PEBP1 (NP_002558.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 21.1 kDa
Database Links
Alternative Names PEBP1Phosphatidylethanolamine-binding protein 1 antibodyPEBP-1 antibodyHCNPpp antibodyNeuropolypeptide h3 antibodyProstatic-binding protein antibodyRaf kinase inhibitor protein antibodyRKIPPEBP1 antibodyPBP antibodyPEBP
Function Binds ATP, opioids and phosphatidylethanolamine, Has lower affinity for phosphatidylinositol and phosphatidylcholine, Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase (By similarity), Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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